Brexit, for once some facts.

Woosh

Trade Member
May 19, 2012
20,339
16,857
Southend on Sea
wooshbikes.co.uk
No JHC I think is correct, from memory that Scottish trial showed that the AZ was slightly more effective at reducing hospitalisations than the Pfizer one.

It had not yet been peer reviewed so I think we need to wait for more information, but I am not too bothered which one is slightly better. They are both excellent at reducing the chance of people becoming seriously ill and having to go into hospital.
Agreed.
Results of Scottish study:

Vaccine dose 1 (7- 13 days) Pfizer 38% AZ 70%
Vaccine dose 1 (14-20 days) Pfizer 60% AZ 74%
Vaccine dose 1 (21-27 days) Pfizer 72% AZ 84%
Vaccine dose 1 (28-34 days) Pfizer 85% AZ 94%
Vaccine dose 1 (35-41 days) Pfizer 68% AZ NA
Vaccine dose 1 (42+ days) Pfizer 64% AZ NA

the study shows the rapid decrease in vaccine effect after only 5-6 weeks.
I wonder what it would be after 12 weeks.
 

Danidl

Esteemed Pedelecer
Sep 29, 2016
8,611
12,256
73
Ireland
"The Oxford-AstraZeneca vaccine has been receiving a lot of attention recently. The EU has been dissatisfied with production hold-ups, while the German health ministry has raised questions over its efficacy in older age groups. As a result, Stiko – the German Standing Committee on Vaccination – has suggested in a draft recommendation that the vaccine should not be given to people over 65.

If Germany does decide not to authorise the vaccine for over-65s, this will be because it considers there were insufficient people over 55 included in the vaccine’s phase 3 trials to give a good estimate of efficacy in older age groups. This is an issue that has been raised before.

In fact, in the peer-reviewed write-up of the Oxford-AstraZeneca trials, the authors admitted that following their tests, “vaccine efficacy in older age groups could not be assessed”. But while this isn’t ideal, it’s not a reason to panic.

Indeed, the European Medicines Agency has now authorised th vaccine for use in Europe in all adults over 18, despite German concerns. The EMA acknowledged that efficacy data for over-55s was lacking, but said that it expected the vaccine to be protective “given that an immune response is seen in this age group and based on experience with other vaccines”."

.
Yes. I am aware of this. Now getting the time line sorted would reduce the hysteria.
1. End of January!!! 29th. . AZ approved as safe by EMA,and requiring authorisation by member states . This has the caveats regarding age as identified.
2. EU !ooks to the warehouses expecting supplies , and only minimal supplies available. Hence the glitch.
3. The 27 countries individual regulatory authorities, read the memo, and note the age caveat. They decide to apportion it where it will do the most good . Not the elderly but the senior front line staff.
In the case of Ireland , that was a double whammy in that ,.a they had expected supplies to be available and b. They had organised logistics so that the aged would get those vaccines in nursing homes from the following Monday. Well no vaccines and even where they available, the distribution was now skewed. The immediate decision was to move the AZ into fulltime careworkers under 60 , and reallocate the Pfizers. We are small and we are flexible and as soon as the AZ arrived it was being used . But even a logistical change like that costs a week. Germans and French are not as flexible, and more formal procedure orientated.
 

Danidl

Esteemed Pedelecer
Sep 29, 2016
8,611
12,256
73
Ireland
Agreed.
Results of Scottish study:

Vaccine dose 1 (7- 13 days) Pfizer 38% AZ 70%
Vaccine dose 1 (14-20 days) Pfizer 60% AZ 74%
Vaccine dose 1 (21-27 days) Pfizer 72% AZ 84%
Vaccine dose 1 (28-34 days) Pfizer 85% AZ 94%
Vaccine dose 1 (35-41 days) Pfizer 68% AZ NA
Vaccine dose 1 (42+ days) Pfizer 64% AZ NA

the study shows the rapid decrease in vaccine effect after only 5-6 weeks.
I wonder what it would be after 12 weeks.
My real fear is that it will facilitate mutant and new strain propagation. There is no evidence that it will or will not, but decades of antibiotic abuse suggests caution.
New Scientist has a very interesting article about an attempt to create a universal CV vaccine , by targeting the composition of the protein spikes on the virus, which apparently is very stable against mutation, and is probably the "unique selling point " for the success of the virus.
 

POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
Agreed.
Results of Scottish study:

Vaccine dose 1 (7- 13 days) Pfizer 38% AZ 70%
Vaccine dose 1 (14-20 days) Pfizer 60% AZ 74%
Vaccine dose 1 (21-27 days) Pfizer 72% AZ 84%
Vaccine dose 1 (28-34 days) Pfizer 85% AZ 94%
Vaccine dose 1 (35-41 days) Pfizer 68% AZ NA
Vaccine dose 1 (42+ days) Pfizer 64% AZ NA

the study shows the rapid decrease in vaccine effect after only 5-6 weeks.
I wonder what it would be after 12 weeks.
100% Bullcrap
 

POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
Yes. I am aware of this. Now getting the time line sorted would reduce the hysteria.
1. End of January!!! 29th. . AZ approved as safe by EMA,and requiring authorisation by member states . This has the caveats regarding age as identified.
2. EU !ooks to the warehouses expecting supplies , and only minimal supplies available. Hence the glitch.
3. The 27 countries individual regulatory authorities, read the memo, and note the age caveat. They decide to apportion it where it will do the most good . Not the elderly but the senior front line staff.
In the case of Ireland , that was a double whammy in that ,.a they had expected supplies to be available and b. They had organised logistics so that the aged would get those vaccines in nursing homes from the following Monday. Well no vaccines and even where they available, the distribution was now skewed. The immediate decision was to move the AZ into fulltime careworkers under 60 , and reallocate the Pfizers. We are small and we are flexible and as soon as the AZ arrived it was being used . But even a logistical change like that costs a week. Germans and French are not as flexible, and more formal procedure orientated.
100% Bullcrap
 

POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
My real fear is that it will facilitate mutant and new strain propagation. There is no evidence that it will or will not, but decades of antibiotic abuse suggests caution.
New Scientist has a very interesting article about an attempt to create a universal CV vaccine , by targeting the composition of the protein spikes on the virus, which apparently is very stable against mutation, and is probably the "unique selling point " for the success of the virus.
mutant strain my arse
 

flecc

Member
Oct 25, 2006
53,158
30,574
mutant strain my arse
Forum Rules & Terms of Use

1. No profanity or obscenities of any kind

3. Freedom of speech does not extend to trolling. Or using the forum to further your own agenda, whether that is personally or commercially driven.

POLLY, you clearly have a personally driven agenda that Covid-19 is faked, despite all the vast amount of evidence to the contrary and the public health damage your argument can do.

Perhaps you should take your argument to social media since you aren't going to convince anyone in here.
.
 

POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
Forum Rules & Terms of Use

1. No profanity or obscenities of any kind

3. Freedom of speech does not extend to trolling. Or using the forum to further your own agenda, whether that is personally or commercially driven.

POLLY, you clearly have a personally driven agenda that Covid-19 is faked, despite all the vast amount of evidence to the contrary and the public health damage your argument can do.

Perhaps you should take your argument to social media since you aren't going to convince anyone in here.
.
Covid-19 is faked
 

Zlatan

Esteemed Pedelecer
Nov 26, 2016
8,086
4,290
Covid-19 is faked
How do you explain what's happening in hospitals Polly...??? Our ICU is working under capacity now but for previous 12 weeks was full of people on ventilators?? Doctors, nurses and everyone involved saying it was Covid??
 
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Zlatan

Esteemed Pedelecer
Nov 26, 2016
8,086
4,290
Covid-19 is faked
To convince anyone you need to offer at least an explanation Polly. I do agree many aspects of it are over reported, exaggerated and generally poorly reported in efforts to either bull up certain aspects or dismiss others. But totally faked?? Come on Polly... Explain.
 
  • Agree
Reactions: flecc

flecc

Member
Oct 25, 2006
53,158
30,574
I've reported POLLY's posts with this comment on the reason:

"Profanity and promotion of a personal agenda that has the potential to harm public health by discouraging belief in Covid-19s existence and discouraging vaccine take-up."
.
 
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