Cycling. Health. Covid. Diet.

[lenny]

The 10 Glucose Goddess Hacks

The Glucose Goddess hacks reduce glucose spikes in everyone: people with and without diabetes. They help improve: cravings for sugar, energy levels, bloating, constant hunger, brain fog, inflammation, and hormones.

www.glucosegoddess.com

https://www.channel4.com/programmes/eat-smart-secrets-of-the-glucose-goddess

 

[lenny]

Virus leads to ‘severe pneumonia in days’ as people claim ‘it’s worse than 2022’
A "mystery" virus outbreak is the talk of Chinese social media, with one report suggesting it's "worse than COVID-19."

Virus leads to ‘severe pneumonia in days’ as people claim ‘it’s worse than 2022’

A "mystery" virus outbreak is the talk of Chinese social media, with one report suggesting it's "worse than COVID-19."

www.express.co.uk

 

[Ghost1951]

Virus leads to ‘severe pneumonia in days’ as people claim ‘it’s worse than 2022’
A "mystery" virus outbreak is the talk of Chinese social media, with one report suggesting it's "worse than COVID-19."

Virus leads to ‘severe pneumonia in days’ as people claim ‘it’s worse than 2022’

A "mystery" virus outbreak is the talk of Chinese social media, with one report suggesting it's "worse than COVID-19."

www.express.co.uk

Very inventive the Chinese....

Sars

Sars-Cov-2

And now this no-name pneumonia.

The WHO reckons they have record of 7 million deaths from sars-cov-2 signed off by medics and that there were probably three times that world wide - so that makes probably 21 million deaths across the world from covid.

They have a remarkable record of generating new and dangerous diseases and letting them get out of control.

I listened to this pair of programmes on BBC sounds today while I was out walking.Worth a listen if you are interested in this sort of thing.

Science In Action - Five years of Covid: Part one - BBC Sounds

Five years on from the emergence of Sars CoV-2, what have we learned?

www.bbc.co.uk

Science In Action - Five years of Covid: Part two - BBC Sounds

Five years on from the emergence of Sars CoV-2, what have we learned?

www.bbc.co.uk

 

[nigelbb]

Very inventive the Chinese....

Sars

Sars-Cov-2

And now this no-name pneumonia.

The WHO reckons they have record of 7 million deaths from sars-cov-2 signed off by medics and that there were probably three times that world wide - so that makes probably 21 million deaths across the world from covid.

They have a remarkable record of generating new and dangerous diseases and letting them get out of control.

I listened to this pair of programmes on BBC sounds today while I was out walking.Worth a listen if you are interested in this sort of thing.

Science In Action - Five years of Covid: Part one - BBC Sounds

Five years on from the emergence of Sars CoV-2, what have we learned?

www.bbc.co.uk

Science In Action - Five years of Covid: Part two - BBC Sounds

Five years on from the emergence of Sars CoV-2, what have we learned?

www.bbc.co.uk

For decades we have known that China is the usual origin for new strains of 'flu. The theory is that pigs, chickens & people all living in close proximity allow new strains to hop between species. It's the same for these other new respiratory viruses. There is no need for dark conspiracies about viruses escaping from labs.

 

[Ghost1951]

For decades we have known that China is the usual origin for new strains of 'flu. The theory is that pigs, chickens & people all living in close proximity allow new strains to hop between species. It's the same for these other new respiratory viruses. There is no need for dark conspiracies about viruses escaping from labs.

https://www.amazon.co.uk/Viral-Search-Covid-19-Alina-Chan/dp/0008487499

 

[Ghost1951]

For decades we have known that China is the usual origin for new strains of 'flu. The theory is that pigs, chickens & people all living in close proximity allow new strains to hop between species. It's the same for these other new respiratory viruses. There is no need for dark conspiracies about viruses escaping from labs.

Very glib.

Are you not at all interested in the fact that the virus emerged in a city which has two virology research labs which we KNOW from grant applications which you can download, were experimenting with gain of function research (it means manipulating viruses so that they can infect human cells) with bat corona viruses?

Are you not interested in the fact that in spite of extremely detailed searches, no wildlife or domestic animal species has been found to have the very close relative of Sars-Covi-2, and that the Wuhan Institute of Virology DID have, and were experimenting with RaTG13 - a bat corona virus from the Hunan caves that has a 96.1 similarity to Sars-Covi-2?

WIV had a large database of viral genomes covering viruses they were working on. Researchers world wide were able to interogate this database right up until around January 2020 when it suddenly went offline.

When SARS spilled over and Mers, near identical viruses were rapidly found in animal reservoirs - thus showing that a natural spill over had occurred through minor natural mutations of the virus code. NOT SO in Sars-Covi-2. No intermediate host has been identified positively. Only unsupported theories exist about civet cats and other animals, but virus samples showing they were infected with Sars-Covi-2 before the pandemic do not exist.

Sars-Covi-2 emerged oven ready to infect human lung tissue in an almost perfect form. This is most unusual and is why when these spill over viruses that you mention DO NOT usually spread easily between people. They only infect people who have massive contact with infectious material on farms butcheries and such places, often killing the recipient, but they do not spread from that person to other people. Sars-Covi-2 was incredibly infectious and flew from person to person so that in weeks it was all over the planet. Viruses that transfer from animals need many generations in human hosts to evolve t spread efficiently. Sars-Covi-2 emerged the perfect virus to infect human hosts.

The Wuhan Institute of Virology WAS experimenting on adapting bat viruses to human tissue through the technique of serial passage. They applied for a grant to do this in 2018 using the funding body Eco Health Alliance of America. NO grant was given, but the lab already had vast resources of finance from the Chinese government, and they had a wide range of bat viruses and were experimenting with them already when they made the grant application.

You can read the grant proposal here. Eco Health Alliance had as their research partner - The Wuhan Institute of Virology.

https://www.researchgate.net/publication/363729325_DRASTIC_-_An_Analysis_of_Project_DEFUSE

Abstract for above research paper:

Abstract
An Analysis of the Project DEFUSE proposal submitted by EcoHealth Alliance [EHA] to the Defense Advanced Research Projects Agency [DARPA] on 3/27/2018; DARPA rejected the proposal, ultimately choosing 5 other groups for its PREEMPT initiative. The proposal describes, in great detail, experiments which could have directly resulted in the SARS-CoV-2 virus that emerged in Wuhan in the fall of 2019; elements of particular concern include the introduction of human proteolytic cleavage sites into SARS-like coronaviruses, the expressed interest in identifying viral strains which could exploit the DC-SIGN pathway, introduction of "key RBD residues" to test ACE2 affinity in humanized mice, and targeted "boosting" [suppression] of bat interferon responses. Given that the initial wild-type SARS-Cov-2 genome contained a Furin Cleavage Site, high hACE2 affinity, DC-SIGN receptors and several ORF components which degrade interferon responses, the existence of the DEFUSE proposal documents raises important questions about the origin of the SARS-CoV-2 virus and the COVID-19 pandemic.

 

[nigelbb]

I don't need to research or bother wasting my time on this as from my point of view it's irrelevant whether it was an escaped engineered or free range virus. The effect was the same.

The old medical adage is that commonest things are commonest. This is usually quoted to medical students & juniors who attribute symptoms to some rare disease when there is a simpler less rarefied diagnosis. On that basis it's most likely a virus that evolved in the wild as that is where these respiratory viruses usually come from.

 

[Ghost1951]

I don't need to research or bother wasting my time on this as from my point of view it's irrelevant whether it was an escaped engineered or free range virus. The effect was the same.

The old medical adage is that commonest things are commonest. This is usually quoted to medical students & juniors who attribute symptoms to some rare disease when there is a simpler less rarefied diagnosis. On that basis it's most likely a virus that evolved in the wild as that is where these respiratory viruses usually come from.

It is odd that you show such a lack of professional curiosity. Rather lazy, actually.

I'll explain why it is important whether the virus emerged naturally as a zoonotic spillover or as a lab leak of an engineered virus.

We KNOW that so called, 'gain of function' research is happening in labs across the world.

We KNOW that labs - especially in China are far from leak proof. SARS escaped from Chinese labs more than once after they got samples to work on and examine. Escapes are not restricted to them either. Porton Down allowed Foot and Mouth to escape their labs in Wiltshire. A decrepit waste pipe from the lab to an incinerator leaked and the virus escaped to a neighbouring field. And these examples are not the only ones. There have been several escapes of dangerous viruses from labs across the world.

If labs are allowed to encourage animal viruses to develop into human pathogenic forms - and they certainly are allowed to do such research, how long will it be before something truly dreadful escapes into the wild?

Having spent some time reading peer reviewed work on this problem, I think that virus manipulation is probably the greatest threat to human civilisation that we face. It is only a matter of time before a civilisation ending pathogen escapes. Global Warming will be as nothing to that in terms of threat to billions of us and to civilisation as a whole..

We were lucky with Sars-Cov-2. It only killed 21 million people.

Pity some medically trained people are too lazy to think about that.

 

[nigelbb]

It is odd that you show such a lack of professional curiosity. Rather lazy, actually.
...
Pity some medically trained people are too lazy to think about that.

Some retired medical people don't care to go down a rabbit hole chasing the origins of the virus. I leave that to far better qualified people than me as I have better uses for my time.

 

[Ghost1951]

Some retired medical people don't care to go down a rabbit hole chasing the origins of the virus. I leave that to far better qualified people than me as I have better uses for my time.

Speaking of 'rabbit holes' - myxomatosis anyone? It had a 99.8% case fatality rate. One Californian strain killed 100% of infected animals.

There is NOTHING to stop some manipulated virus emerging from a gain of function experiment that would be as dangerous as that. As for 'Better use of ' your time..... I'm sure guzzling gas in your old Range Rover is far better than looking into something as trivial as why we allow researchers world wide to manipulate viruses that can not infect humans so that they can.

Gain-of-function pathogen research is controversial and widespread. Can it be regulated?

A new study looks at decades of gain-of-function pathogen studies and concludes that the controversial research field will be difficult to regulate. It comes as activists and politicians are seeking to ban the practice and as the federal government is considering new restrictions.

thebulletin.org

 

[flecc]

Having spent some time reading peer reviewed work on this problem, I think that virus manipulation is probably the greatest threat to human civilisation that we face. It is only a matter of time before a species ending pathogen escapes. Global Warming will be as nothing to that in terms of threat to billions of us and to civilisation as a whole..

Best prospect for the future of biology on this planet that I've seen in many years, terminating the worst species of all by far, the only one that seriously threatens all other life.
.

 

[Ghost1951]

Best prospect for the future of biology on this planet that I've seen in many years, terminating the worst species of all by far, the one that seriously threatens all other life.
.

That's a rather draconian attitude though, isn't it?

I can think of many ways in which the irresponsible behaviour of human beings might be improved, or mitigated, that don't involve the extermination of the species.

 

[flecc]

I can think of many ways in which the irresponsible behaviour of human beings might be improved, or mitigated, that don't involve the extermination of the species.

Improvement or mitigation don't solve the problem, which is that our development of the mind, seemingly beyond limits, can only end one way, self destruction.

The danger with this is that we take all other life with us. Best get rid of the cause first.
.

 

[saneagle]

For decades we have known that China is the usual origin for new strains of 'flu. The theory is that pigs, chickens & people all living in close proximity allow new strains to hop between species. It's the same for these other new respiratory viruses. There is no need for dark conspiracies about viruses escaping from labs.

It's only in the last couple of hundred years that man has managed to separate from that lifestyle. If what you're saying were true, humans would have been wiped out by every type of virus many times over. Try using some logic instead of what you see on the BBC or in the Guardian.

 

[nigelbb]

It's only in the last couple of hundred years that man has managed to separate from that lifestyle. If what you're saying were true, humans would have been wiped out by every type of virus many times over. Try using some logic instead of what you see on the BBC or in the Guardian.

I'm using my knowledge of the origin of diseases especially 'flu. I learned this stuff from textbooks not random nut jobs on YouTube. None of these respiratory viruses will wipe out humans. Even SARS only had death rate of 11%. MERS which didn't arise in China has a death rate of up to 35% but still not 100%. Even Ebola has a mortality of 25-90%. None of them completely destroy the human race.

 

[Ghost1951]

I'm using my knowledge of the origin of diseases especially 'flu. I learned this stuff from textbooks not random nut jobs on YouTube. None of these respiratory viruses will wipe out humans. Even SARS only had death rate of 11%. MERS which didn't arise in China has a death rate of up to 35% but still not 100%. Even Ebola has a mortality of 25-90%. None of them completely destroy the human race.

You know nothing about who I am or where I came by information.

The idea that the genetic manipulation of viruses could not produce a very dangerous outcome is glib, stupid and very ill-informed.

Gain of function research is a branch of virology which aims to do good - getting ahead of emerging threats - viruses which may not need many genetic changes to become infectious to us and therefore become dangerous, but is, I believe responsible for the emergence of Sars-Covi-2. and COULD HAVE produced a far more dangerous pathogen. We are fortunate that it did not.

Your likening of sars-covi-2 to influenza is a classic error. Much of the response to the emergence of this virus in 2019 was in fact based on influenza planning. That was the expected next pandemic, but it was not what came out of that lab - probably when a lab worker was accidentally and unknowingly infected. They were working in Wuhan with only level 2 containment on adapted bat corona viruses, and out it came. It could have been much worse, but it still killed probably about 21 million people world wide and has left many more in a poor state.

Maybe you ought to refresh your information base - retired or not. You should do so.

By the way - I don't think I ever said that the threat of modified viruses would destroy the human race.[NOTE1] I think I said it could end our civilisation. This may be unlikely, but it is a possibility when people are allowed to modify viruses to make currently non human viruses able to infect human tissue. I think that deliberately making animal viruses able to infect humans is the most gross stupidity we have ever engaged in.

Try googling for a list of dangerous lab escapes and you will see why I am concerned.

What happens if an engineered virus escapes the lab?

Since the 1970s, researchers have engineered superbugs. While this research could help us prepare for future outbreaks, the stakes of this work are extremely high: if even one dangerous virus escaped a lab, it could cause a global pandemic. So, what can we do to minimize risk? And is the...

www.ted.com

NOTE1 - EDIT:

I just checked back and this statement is mistaken. I DID in fact say species ending. That was a mistake and I have corrected the original post.

 

[lenny]

Ketogenic Diet in the Treatment of Gliomas and Glioblastomas

https://pmc.ncbi.nlm.nih.gov/articles/PMC9504425/

 

[lenny]

Diets high in advanced glycation end products promote insulin resistance

https://examine.com/research-feed/study/9kjAb0/

 

[lenny]

COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals

COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals - PubMed

This multi-country analysis confirmed pre-established safety signals for myocarditis, pericarditis, Guillain-Barré syndrome, and cerebral venous sinus thrombosis. Other potential safety signals that require further investigation were identified.

pubmed.ncbi.nlm.nih.gov

 

[lenny]

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

https://www.nature.com/articles/s41591-024-03345-4