it's more like the cross-species barrier that kept us alive in that time and even now.
Brexit, for once some facts.
- Thread starter flecc
- Start date
That’s probably because we didn’t move around as much. Viruses would wipe out a much more localised and less mobile community. Then the virus itself would die out due to lack of new people to infect.
True,
and compare that to today, europe just a couple of minutes ago and there`s supposed to be a pandemic - yeah right!
We have that same condition now since we are nowhere near occupying all of the planet or moving as much as we might.
It's all part of immunity, some survive to carry us forward, even if it's only a single Adam and Eve it means there's always immunity.
.
most of us are not immune to the common cold virus like the adenovirus (very similar to SARS-COV2) that is used to make covid vaccines. It's just that the adenovirus does not kill.
Cross-species barrier is much more general though.
Yes, but in olden days the Coronavirus would have stayed local to Wuhan and wiped the resident population out. It would not have traveled to London on a plane.
It would have got here eventually via a slow boat according to B. Crosby et al...
Still much of humanity was relatively isolated once it spread far and wide around the globe, only as we changed from hunter gatherers to more settled ways in crammed communities and the first cities, and embarked upon trading over increasing distances, then over housands of years made trans global explorations and colonisations did we meet long lost branches of other humans to spread novel lurgy bugs. Then yes nowadays airliners facilitate the mega speedy spreaders in days rather than weeks, or months.
There have been nearly 50 million recorded cases of Covid 19 world wide and probably many times more that have not been recorded and yet there have only been a tiny amount of re-infections. This would suggest that at least for several months after catching the virus the chances of re-infection are very small.
It is too early to know how long this apparent immunity lasts but some (not yet peer reviewed) research in the link below provides strong evidence of sustained defence in people who recover from the virus.
www.theguardian.com
It is too early to know how long this apparent immunity lasts but some (not yet peer reviewed) research in the link below provides strong evidence of sustained defence in people who recover from the virus.
Covid immune response faster and stronger post-infection, scientists say
Strongest evidence yet found of sustained defence in people who recover from coronavirus
www.theguardian.com
What studies? How many other studies show the opposite?
How much actual research have you done before forming that opinion?
I see testing is still world beating:
Operation Moonshot: rapid Covid test missed over 50% of cases in pilot
Exclusive: mass-testing experts say tests should not be widely used in hospitals or care homes
https://www.theguardian.com/world/2020/nov/05/operation-moonshot-rapid-covid-test-missed-over-50-of-cases-in-pilot
Has anyone else managed to miss that large a percentage of cases?
Operation Moonshot: rapid Covid test missed over 50% of cases in pilot
Exclusive: mass-testing experts say tests should not be widely used in hospitals or care homes
https://www.theguardian.com/world/2020/nov/05/operation-moonshot-rapid-covid-test-missed-over-50-of-cases-in-pilot
Has anyone else managed to miss that large a percentage of cases?
OK - from the report I'll pick out these things:
Largest COVID-19 antibody testing programme publishes findings on antibody response over time
Findings from Imperial College London and Ipsos MORI show the number of people with antibodies fell by 26.5% over 3 months.www.gov.uk
"The results suggest that people who did not show symptoms of COVID-19 are likely to lose detectable antibodies sooner than those who did show symptoms. The findings also show the loss of antibodies was slower in 18 to 24 year-olds compared to those aged 75 and over."
and:
"It remains unclear whether antibodies provide any effective level of immunity or, if such immunity exists, for how long it might last. "
Right - so they still don't know if these so-called 'antibodies' are the key to providing immunity. There are other factors they don't know about.
Plus - one of the main things we still have no idea about is how come some people get the virus and it does f*** all to them (eg Trump) - versus people who get it and come down really bad with it or die. WE JUST DO NOT KNOW. We do not know enough about this thing yet.
I would not jump to conclusions. Who knows what we'll find out about this thing in the weeks months and years to come.
I wonder which Tory MP or ministers wife, brother, sister, other relative or mate they went to school with owns the company mentioned in the article that makes the test machines.
I half agree, just came back from a run, as I walked back noticed many common pippistrelle bats darting about happily above my head. England can be pretty. The Westminster system never worked. I can accept that. But not a complete psychopath like boris pilfering billions for cronies. Spent some time in africa where a run like the one tonight would be impossible (one would be worryingly more than mugged). I worry about what will happen to post covid brexit uk with its xenophobes and populist idiots. Social fabric can tear and things can go very bad very quickly.
We don't know in the sense not all factors are fully identified. But there has been work which has identified some factors of significance:
Air pollution - probably particulates and nitrogen oxides.
Low vitamin D.
Low triiodothyronine in lungs.
Genome - possibly very minor differences.
Though obviously we don't yet know enough.
Should have got Arthur C Clarke in as a consultant...
Plus a big unknown if it further mutates and is capable of coming around again ... There's Denmark culling 15 million mutated minky coronavirus which infected folk
Denmark to cull up to 17 million mink amid coronavirus fears
Cases of a mutated strain of Covid-19 have been detected that may undermine future vaccines.
www.bbc.co.uk
by design though. It's like a mountain range between two countries.
No need to post your T-cell troops on it.
I thought we were talking about acquired immunity.
I'll look them up and come back to you later.
Here is an interesting quote explaining how some people having a strong immune response and still are very ill:
quote:
In a study accepted to the journal Cell, tenOever and his colleagues found that SARS-CoV-2 appears to block this interferon signal, meaning it messes with the cell's second job. So the first job — the call for immune system reinforcement — works just fine, but the cells in the lungs don't enter defensive mode and so remain vulnerable to viral infection.
"It just keeps replicating in your lungs, and replicating in your lungs and all the while you keep calling in for more reinforcements," tenOever told Live Science.
In many people, even this crippled immune response is enough to beat back the virus. But for reasons not yet fully understood, some people enter a vicious cycle. As the virus keeps replicating, the immune army that arrives to battle it starts doing its job: attacking infected cells, digesting debris and chemicals spewed out by dying cells, even killing nearby cells in an attempt to staunch the damage. Unfortunately, if the virus continues to penetrate lung cells, this army may do more damage than good. The lung tissue becomes hopelessly inflamed; the blood vessels begin to leak fluids into the lung; and the patient begins to drown on dry land. This seems to be the reason that some people become severely ill a couple of weeks after their initial infections, tenOever said.
"At that point, it's not about what the virus has done," he said. "At that point, it's about controlling the severe inflammation."
This cycle is very bad news. But there is a glimmer of hope in the findings. Because the system that calls in the army of immune cells works fine, it seems likely that survivors of COVID-19 will retain immunity to the virus. And indeed, studies have found high levels of antibodies to SARS-CoV-2 in recently recovered patients. Antibodies are proteins made by immune system cells called B cells. They stick around in the blood post-infection and can bind to the virus, either neutralizing it directly or marking it for destruction by other immune cells.