Brexit, for once some facts.

OxygenJames

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I half agree, just came back from a run, as I walked back noticed many common pippistrelle bats darting about happily above my head. England can be pretty. The Westminster system never worked. I can accept that. But not a complete psychopath like boris pilfering billions for cronies. Spent some time in africa where a run like the one tonight would be impossible (one would be worryingly more than mugged). I worry about what will happen to post covid brexit uk with its xenophobes and populist idiots. Social fabric can tear and things can go very bad very quickly.
Which is why I like to walk in the woods with my dog - you can forget about all that for a while.

What's wrong with right now unless you think about it? Most of the time nothing.
 
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OxygenJames

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I'll look them up and come back to you later.

Here is an interesting quote explaining how some people having a strong immune response and still are very ill:
quote:
In a study accepted to the journal Cell, tenOever and his colleagues found that SARS-CoV-2 appears to block this interferon signal, meaning it messes with the cell's second job. So the first job — the call for immune system reinforcement — works just fine, but the cells in the lungs don't enter defensive mode and so remain vulnerable to viral infection.
"It just keeps replicating in your lungs, and replicating in your lungs and all the while you keep calling in for more reinforcements," tenOever told Live Science.
In many people, even this crippled immune response is enough to beat back the virus. But for reasons not yet fully understood, some people enter a vicious cycle. As the virus keeps replicating, the immune army that arrives to battle it starts doing its job: attacking infected cells, digesting debris and chemicals spewed out by dying cells, even killing nearby cells in an attempt to staunch the damage. Unfortunately, if the virus continues to penetrate lung cells, this army may do more damage than good. The lung tissue becomes hopelessly inflamed; the blood vessels begin to leak fluids into the lung; and the patient begins to drown on dry land. This seems to be the reason that some people become severely ill a couple of weeks after their initial infections, tenOever said.
"At that point, it's not about what the virus has done," he said. "At that point, it's about controlling the severe inflammation."
This cycle is very bad news. But there is a glimmer of hope in the findings. Because the system that calls in the army of immune cells works fine, it seems likely that survivors of COVID-19 will retain immunity to the virus. And indeed, studies have found high levels of antibodies to SARS-CoV-2 in recently recovered patients. Antibodies are proteins made by immune system cells called B cells. They stick around in the blood post-infection and can bind to the virus, either neutralizing it directly or marking it for destruction by other immune cells.
Right - sometimes it's the 'immune response' itself that is the actual problem. The body over-reacts to the allergen whilst other people's systems just ignore it.
 

OxygenJames

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Plus a big unknown if it further mutates and is capable of coming around again ... There's Denmark culling 15 million mutated minky coronavirus which infected folk
Right. Like HIV which mutates all the time and why there is no vaccine - but HIV is now not a threat because there are other drugs that can deal with it.

There is evidence that COVID also mutates - even more than HIV so it may well be no vaccine will work but science will find other ways to manage the disease so it is not a problem (like with HIV).
 

oyster

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But for reasons not yet fully understood, some people enter a vicious cycle.
Not making a claim this is a full explanation, but one tiny element.

The thyroid hormone T3 is effectively wiped out in lungs during serious Covid-19 infection. It is well-known that many diseases result in Non-Thyroid Illness Syndrome where T3 levels drop but the mechanisms which we would expect to correct that do not come into play as usual.

T3 is a fundamental element required for cells to work properly - both genomically and non-genomically. Lack of T3 might be why they cannot overcome the virus.

The "standard" view has been that low T3 is a way of turning down the wick when your body is handling infection and inflammation. However, there are several challengers of that point of view - who claim that maintaining T3 levels could even be used as a medical intervention. Currently a trial is going on effectively squirting T3 into the lungs of Covid-19 patients.
 

oyster

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Right. Like HIV which mutates all the time and why there is no vaccine - but HIV is now not a threat because there are other drugs that can deal with it.

There is evidence that COVID also mutates - even more than HIV so it may well be no vaccine will work but science will find other ways to manage the disease so it is not a problem (like with HIV).
In thyroid disease, which in medical treatment terms effectively started in about 1890, some of the early work was astonishing. By 1960, both the main thyroid hormones (T4 and T3) had been synthesised and were available in tablet form.

The medical establishment saw these synthetic forms as being superior to the previous treatment - dried and powdered animal thyroid. Trouble was, they insisted that T4 alone was adequate when the animal products contained T4 and T3. There has never been proper research to support change from animal thyroid to synthetic. A view that is only now starting to be over-turned by some research. (But has long been challenged by patients who did not do well on T4 only.)

A big element of this was poor science and medical practice. But another part was the cost with T3 often being much more expensive than T4.

I meander round that story because even if we have medicines which work as anti-virals (or symptomatic treatments) for Covid-19, there is the little issue of getting them to those who need them.

Maybe we in the western countries manage to afford whatever medicines are found. But it could become yet another case where the world is split.

By the way, did anyone notice that they are looking as Ivermectin as an anti-viral against Covid-19? A medicine used against parasistes and supplied at no charge by at least one major pharmaceutical company to African countries.
 

Barry Shittpeas

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Barry Shittpeas

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US presidential election latest:
Biden set to win by tonight.

The Dems need to get all of those unsigned postal votes signed by the 17:00 deadline today. (In the U.K., these are known as Spoilt Ballot Papers). I’m not sure how you get a corpse to sign a ballot paper though. Could be tricky. I’m sure the Dems will find a way, after all, they managed to get a corpse to stand for president.
 

Woosh

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Biden was 463 votes behind Trump in Georgia about half an hour ago.
Biden is also going to take Pennsylvania. He's only 18,000 votes behind Trump.
Biden will be well ahead in both by lunch time.
 
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OxygenJames

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The Dems need to get all of those unsigned postal votes signed by the 17:00 deadline today. (In the U.K., these are known as Spoilt Ballot Papers). I’m not sure how you get a corpse to sign a ballot paper though. Could be tricky. I’m sure the Dems will find a way, after all, they managed to get a corpse to stand for president.
Seems like you've not only been taken in by that fake Wisconsin 'voting numbers' fraud (that screenshot you sent in which has been shown to be completely false) - but you've also been brainwashed into the idea that this election is being fixed.

Bad boy Barry!

Anybody who knows anything about the historical influx of votes in the US (I have a suspicion you are not one of those people) - will be aware that late votes in all the mid-western states poll strongly for the democrats. It was like that in 2008 and 2012 and 2016 - and so it is proving this year. Democrats tend to vote by post WAY more than Republicans - and what with COVID this is even more true this time around.

So come on Barry - get with the plot and stop sending in nonsense posts or I will have to assume you're an OG stooge!
 

OxygenJames

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Biden was 463 votes behind Trump in Georgia about half an hour ago.
Biden is also going to take Pennsylvania. He's only 18,000 votes behind Trump.
Biden will be well ahead in both by lunch time.
Hmmmm. My original bet was Trump would hold Pennsylvania - looks like I could be wrong and I really don't like being wrong.
 

Woosh

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Hmmmm. My original bet was Trump would hold Pennsylvania - looks like I could be wrong and I really don't like being wrong.
It was Christian Fraser on BBC News 24 on election night.
the BBC's Pennsylvania swingometer showed 1.3% in favour of Biden based on exit polls.
He only needs about 0.6% to win so Biden could end up winning with a margin of about 0.5% - 1%.
Still, there are 9000 military ballots to be counted last.
I must say the BBC has a very good team of statisticians.
 
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Woosh

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Biden takes the lead in Georgia a few minutes ago.
All eyes are now on Pennsylvania.
Newt Gingrich, interviewed by Fox News, wanted the FBI arrest all election workers in Georgia and the local legislature throw out the election result.
 
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Barry Shittpeas

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Seems like you've not only been taken in by that fake Wisconsin 'voting numbers' fraud (that screenshot you sent in which has been shown to be completely false) - but you've also been brainwashed into the idea that this election is being fixed.

Bad boy Barry!

Anybody who knows anything about the historical influx of votes in the US (I have a suspicion you are not one of those people) - will be aware that late votes in all the mid-western states poll strongly for the democrats. It was like that in 2008 and 2012 and 2016 - and so it is proving this year. Democrats tend to vote by post WAY more than Republicans - and what with COVID this is even more true this time around.

So come on Barry - get with the plot and stop sending in nonsense posts or I will have to assume you're an OG stooge!
I don’t think I posted a screenshot. Could be wrong, but I don’t think I did.

I believe that it is within the US election rules to sign a postal ballot paper after sending it in, if you forgot to do it before posting. The deadline is 17:00 local for doing that. Voters can go on-line to check if their paper needs a signature. This applies equally to both sides, Reps and Dems.

So my original post wasn’t total BS :p
 

Barry Shittpeas

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In a bad tempered rage, could Trump launch a nuclear strike on North Korea? A sort of farewell present for Biden to clear up.

Asking for a friend.
 
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oyster

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I hope Trump doesn't try to copy this Putin ploy...

Russian MPs consider lifetime immunity for former presidents
Second bill in a week prompts talk of whether Putin could be preparing for retirement
Russian lawmakers have introduced a bill to parliament that would give Vladimir Putin lifetime immunity from prosecution if and when he decides to leave office.


The draft bill would give a former president immunity from criminal prosecution for any offences committed during his lifetime. A supermajority of lawmakers would be required to revoke the protections. Currently, ex-presidents are protected for actions taken only while they were in office.

https://www.theguardian.com/world/2020/nov/05/russian-mps-consider-lifetime-immunity-for-former-presidents-putin

Though he obviously already considers himself in that position.

Mind, maybe even trying to achieve that would help to make his house fall in?
 

oyster

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In a bad tempered rage, could Trump launch a nuclear strike on North Korea? A sort of farewell present for Biden to clear up.

Asking for a friend.
I strongly suspect people with slightly deeper connections to the US military will have considered this. I wonder what would actually happen?

Hubris syndrome: An acquired personality disorder? A study of US Presidents and UK Prime Ministers over the last 100 years
https://academic.oup.com/brain/article/132/5/1396/354862
 
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