Brexit, for once some facts.

Jesus H Christ

Esteemed Pedelecer
Dec 31, 2020
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Can't you find a smaller version of that silly image so it doesn't waste so much screen space, please?
I’m not promising anything, but I’ll see what I can do. Compromising the safety of forum members isn’t something I am comfortable with, so going forwards, a visual warning of some sort will be necessary.
 
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oyster

Esteemed Pedelecer
Nov 7, 2017
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The question as to whether the common cold helps in fighting Covid-19 is addressed, again, here:

“We have now proven that, in some people, pre-existing T cell memory against common cold coronaviruses can cross-recognize SARS-CoV-2, down to the exact molecular structures,” Weiskopf says. “This could help explain why some people show milder symptoms of disease while others get severely sick.”

Still rather too much "dunno" for my liking.

40601
 

Danidl

Esteemed Pedelecer
Sep 29, 2016
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Ireland
The thinking and decisions in Ireland are ..
1. Any of the vaccines are much better than none.
2. The AZ vaccine will by preference NOT be given to 70+ aged persons. The reason being that there is insufficient evidence that it is effective .. Not evidence that it is ineffective. Whereas there is currently ample evidence that the mRNA types are highly effective in the 70+. It is expected that with more data from the UK, that decision will be revised.
3 There is no plan to extend the interval between doses beyond the recommended EMA durations.

The Chair of the Immunization Qualification Board, makes the point that all these are moving targets and as more data is crunched from around the world.. including of course the UK, they are subject to change.
In additional news, the Germans are setting up a plant to manufacture the Russian Sputnik vaccine, for use in Europe.
While the number of new infections is declining, the number of deaths per day is now at its highest yet at 101. Note.. we did have a much higher number reported in a single day during the first wave, but that was including figures which had been omitted on earlier days.
 

oldgroaner

Esteemed Pedelecer
Nov 15, 2015
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You’ve not made any suggestions. Your specialist subjects are criticism, undermining and obstruction.
Not reading my posts are you?
I suggested
Standardised masks of proven protection
Lockdown at the right time for the right length
Not fooling around with the Vaccine dosage regime

Most important suggestions
Get rid of this Fascist Monty Python tribute act purporting to be the Government
Rejoin the EU as fast as possible
 
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oyster

Esteemed Pedelecer
Nov 7, 2017
10,422
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West West Wales
The thinking and decisions in Ireland are ..
1. Any of the vaccines are much better than none.
2. The AZ vaccine will by preference NOT be given to 70+ aged persons. The reason being that there is insufficient evidence that it is effective .. Not evidence that it is ineffective. Whereas there is currently ample evidence that the mRNA types are highly effective in the 70+. It is expected that with more data from the UK, that decision will be revised.
3 There is no plan to extend the interval between doses beyond the recommended EMA durations.

The Chair of the Immunization Qualification Board, makes the point that all these are moving targets and as more data is crunched from around the world.. including of course the UK, they are subject to change.
In additional news, the Germans are setting up a plant to manufacture the Russian Sputnik vaccine, for use in Europe.
While the number of new infections is declining, the number of deaths per day is now at its highest yet at 101. Note.. we did have a much higher number reported in a single day during the first wave, but that was including figures which had been omitted on earlier days.
Meanwhile, back in Blighty...

Volunteers are being sought for a world-first Oxford trial giving a first dose of one vaccine type and a second dose of another. It will recruit 820 people over the age of 50 to receive a first dose of either the Oxford/AstraZeneca or Pfizer/BioNTech vaccine. Some will later get an alternative second vaccine; others will get the same again. Experts say it could make vaccine delivery more flexible and even produce a more potent immunity.

Are they really looking for greater potency? Or potency against a wider range of mutated variations?
 

oldgroaner

Esteemed Pedelecer
Nov 15, 2015
23,461
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Meanwhile, back in Blighty...

Volunteers are being sought for a world-first Oxford trial giving a first dose of one vaccine type and a second dose of another. It will recruit 820 people over the age of 50 to receive a first dose of either the Oxford/AstraZeneca or Pfizer/BioNTech vaccine. Some will later get an alternative second vaccine; others will get the same again. Experts say it could make vaccine delivery more flexible and even produce a more potent immunity.

Are they really looking for greater potency? Or potency against a wider range of mutated variations?
More likely to be able to make Bogus "World beating research" claims :D
 
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oyster

Esteemed Pedelecer
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Wicky

Esteemed Pedelecer
Feb 12, 2014
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www.jhepburn.co.uk
Are they really looking for greater potency? Or potency against a wider range of mutated variations?
Pragmatism based on potential supply issues

Its lead researcher, Dr Matthew Snape, associate professor in paediatrics and vaccinology at the University of Oxford, tells BBC's Radio 4 Today programme the study is driven by a desire to improve "flexibility in vaccine delivery".

He says: "If somebody turns up to have their second vaccine and they've already received, say, the Pfizer vaccine and it's not available that day then can they receive the Oxford vaccine as an alternative? And vice versa, of course.

Any enhanced antibody response is a handy consequence. As for dealing with mutated versions known and unknown goodness knows - it's all a work in progress on so many fronts.
 

oyster

Esteemed Pedelecer
Nov 7, 2017
10,422
14,609
West West Wales
Pragmatism based on potential supply issues

Its lead researcher, Dr Matthew Snape, associate professor in paediatrics and vaccinology at the University of Oxford, tells BBC's Radio 4 Today programme the study is driven by a desire to improve "flexibility in vaccine delivery".

He says: "If somebody turns up to have their second vaccine and they've already received, say, the Pfizer vaccine and it's not available that day then can they receive the Oxford vaccine as an alternative? And vice versa, of course.
That makes sense - and I agree it needs researching. It was specifically the "even produce a more potent immunity" I wondered about.
 

Jesus H Christ

Esteemed Pedelecer
Dec 31, 2020
1,363
2,206
Not reading my posts are you?
I suggested
Standardised masks of proven protection
Lockdown at the right time for the right length
Not fooling around with the Vaccine dosage regime

Most important suggestions
Get rid of this Fascist Monty Python tribute act purporting to be the Government
Rejoin the EU as fast as possible
Points 1 and 2, I agree with. But point 1 would have been impossible at the time. There was a global shortage of mask, medical agencies across the globe couldn’t get them. They should have encouraged people to use a face covering much earlier. It was pretty obvious even a home made one would be better at reducing droplets than nothing at all.

Johnson has been late with every decision, waiting until he has no choice but to take it. He’s doing it right now with border control. Corbyn would have been worse, he couldn’t decide if he wanted Brexit or not. If we could wind the clock back to December 2019, I’d vote for Johnson 20 times over. We’d be looking at 250000 dead if Corby had been at the helm.
 
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Jesus H Christ

Esteemed Pedelecer
Dec 31, 2020
1,363
2,206
Meanwhile, back in Blighty...

Volunteers are being sought for a world-first Oxford trial giving a first dose of one vaccine type and a second dose of another. It will recruit 820 people over the age of 50 to receive a first dose of either the Oxford/AstraZeneca or Pfizer/BioNTech vaccine. Some will later get an alternative second vaccine; others will get the same again. Experts say it could make vaccine delivery more flexible and even produce a more potent immunity.

Are they really looking for greater potency? Or potency against a wider range of mutated variations?
I’d volunteer for this if I could. It’s a great idea. The U.K. helping our friends across the world again. Excellent.
 

oyster

Esteemed Pedelecer
Nov 7, 2017
10,422
14,609
West West Wales
Points 1 and 2, I agree with. But point 1 would have been impossible at the time. There was a global shortage of mask, medical agencies across the globe couldn’t get them. They should have encountered people to use a face covering much earlier. It was pretty obvious even a home made one would be better at reducing droplets than nothing at all.

Johnson has been late with every decision, waiting until he has no choice but to take it. He’s doing it right now with border control. Corbyn would have been worse, he couldn’t decide if he wanted Brexit or not. If we could wind the clock back to December 2019, I’d vote for Johnson 20 times over. We’d be looking at 250000 dead if Corby had been at the helm.
Perhaps we'd all have been expected to go to work on our allotments? Help address the food supply issues, get fitter, increase our vitamin D levels, avoid (some) shopping, ...
 

oyster

Esteemed Pedelecer
Nov 7, 2017
10,422
14,609
West West Wales
Or more likely just the convenience of being able to give anything as the second dose.
.
I think that was what was meant by "more flexible" - and I agree that is a good and proper aim - so long as no-one gets shafted by being a volunteer.
 

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