That's only if the battery BMS/charger combination pushed the battery to 42 volts. Those I've had only reach 41 volts full charge and from what I've seen in member's posts that is much more common than 42 volts.
In other words the design is safe for the battery to be fully charged without severely stressing it. Equally e-bikes usually cuts out at about 32 volts low charge, once again by design to protect, since the battery could be discharged more. For most users the gain in life from trying to improve on this built-in protection is probably minimal.
Playing about with charging routines I think a bit like trying to get the maximum possible mpg from one's car, only possible with a lot more hassle and sometimes even spoiling the pleasure of using the vehicle.
That's a fair point.
However, my point is different: my point is that for a DIYer, it makes sense to overbuild the battery, with many cells (maybe cheap ones).
The reason is:
1. More capacity outright; this is a good reason already
2. Charging less often, which leads to less time at the dangerous 4.2V area
3. More time at non-extreme SOC levels
4. It takes more days to finish a cycle, and a big part of cell life is the amount of cycles, so mechanically the battery lasts longer
5. The biker can do its usual trips without bothering about capacity (the battery has more capacity than before, even though the biker does not use the full capacity anymore; both effects should approximately cancel out each other), while remaining at safe SOC levels all time time
Of course, this has its own problems: price (but 18650 cells are cheap already), building complexity (it is not easy to build a battery from scratch, at least for me ... granted, I am not knowledgeable enough), location (there is no other way than putting a big battery inside the triangle frame, and this requires either polycarbonate style or directly soldering steel or alloy).