Brexit, for once some facts.

Woosh

Trade Member
May 19, 2012
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wooshbikes.co.uk
I’m sorry but you and Danidl are posting on here in a manner which suggests that you believe you have greater knowledge than the experts. It’s dangerous. It’s foolish.
you are confused again.
I copied and pasted numbers that I found on the internet.
The knowledge/expertise isn't mine, I understand what the numbers mean - that's all.
 

oldgroaner

Esteemed Pedelecer
Nov 15, 2015
23,461
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The Danes are ridiculous. They all walk around in capes made out of bacon and wear pastry hats. Take no notice.

JVT is who you should listen to. He was right about the Oxford vaccine being safe.
I have never said it wasn't! simply reported ongoing results, you made the rest of what you imagined was my opinion to fit your agenda.
Why don't you want to be aware of the research being carried out?
They have discovered that in some cases extending the interval fails to give good results: we need to be aware of that and not bury our heads in the sand
 
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jonathan.agnew

Esteemed Pedelecer
Dec 27, 2018
2,400
3,381
I sometimes can't quite believe what I read in here.
Some people are excusing, actually justifying what has been a terrible vaccine deployment, generally across EU and more specifically in France. People judge in splendid isolation, sat here in UK having had perhaps both vaccines and at least one.
I, m French, I was born and brought up in a relatively wealthy area of Paris. I moved to Devon years ago with my English husband.
Both my parents are secluded away in care homes in Paris. Neither have had vaccine. Neither have seen either me or other siblings or grand children for at least 6 months. Both think this situation is worse than the occupation they lived through during war.
Their fear is not just of dying of covid but of dying before seeing any semblance of normal life, like meals out, visits from kids etc. Any delay, no matter how short is catastrophic for them. They both want the vaccine and as yet have seen no sign of getting one. Yet, somehow folk on here think EU and France have done a fair job.
My husband's father had his first vaccine on 28th January, his second yesterday. He has seen grandkids and is planning trips out and visits. The two situations can not be compared. The UK has without doubt done a fantastic job with vaccine roll out. Those benefitting from it should appreciate the fact and stop moaning about single jab. Some would love to be in that position.
I (under normal circumstances) live in france/Italy much of the year. I think you are discounting the uk's overall performance over the pandemic. Which may be a mistake. We are most definitely not out of the woods yet and theres some solid reasons (around lack of governance) as to why we have higher death rates than europe from covid.
 
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flecc

Member
Oct 25, 2006
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I think that’s the biggest load of horse shite you have posted to date.
Stop attacking well meaning people posting reasonably and have a look at the real enemies instead.

Such as Chainring's thread also in the Charging Post, in particular look at the comments from all the POLLY types that are under the video, believing the vaccines are a dangerous government scam designed to harm us.

LINK
.
 
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POLLY

Pedelecer
Aug 10, 2016
188
272
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you really exaggerated.
It's like someone stops taking aspirin and uses paracetamol instead.
None of the AZ vaccine has been wasted by this action.
some 11 countries suspend temporarily the AZ vaccine but still use other vaccines.
They should be understood, appreciated even for making an effort. What do we do in the mean time? Denying the possible link although the facts are there, the makers of the vaccines themselves specifically look for blood clots in their phase 3 trials. Now they can access a lot more clinical data to further their research. WHO and EMA have always made the case by setting the benefits versus costs which nobody denies.
100% bull crap
 
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POLLY

Pedelecer
Aug 10, 2016
188
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The worst possible effect of a clot is one person dead.

The worst possible effect of not vaccinating is that person dying (as identified, at a greater rate than from clots - if the figures are accurate). And also those infected by that person. And on and on...

Ironically, clots can also be a result of Covid-19 itself. If the same people are susceptible both to dying from clots after vaccination and to dying from clots due to Covid-19, we'd have to check whether their chances of dying from a clot go up or down by being vaccinated.
100% bull crap
 
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oyster

Esteemed Pedelecer
Nov 7, 2017
10,422
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I checked and the results were reassuring that this is not uncommon, here is a link

Winchester Hospital: Intramuscular injection

Hope that helps a little, wish her well on behalf of all one here
Regards
OG
That document says: "Hold the syringe the way you would a pencil. "

Given some of the bizarre ways I've seen people grasp writing implements, that is a questionable description.
 

POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
..From BMJ 21 Jan...

"AstraZeneca and Johnson & Johnson have committed to not making a profit from the pandemic, while Moderna and Pfizer did not. AstraZeneca reserved the right, however, to declare the pandemic phase over and take profits from later vaccine sales."
Someone on this site, Oyster?, Woosh? Indicated that AZ would be defining July as that date.

The BMJ article .. extracted from this article....


A string of revelations about vaccine prices has focused attention on a practice considered normal in the drug industry but often frowned on elsewhere: charging different prices to different customers for the same product.

South Africa’s government found itself on the defensive this week after a senior health official revealed that 1.5 million doses of the Oxford and AstraZeneca vaccine just purchased for use among health workers would cost $5.25 (£3.84; €4.32) a dose, more than twice what the European Union is paying at $2.15.

The EU figure is known because Belgium’s budget secretary inadvertently revealed the EU’s negotiated prices for every major vaccine on Twitter last month.1 The EU had undertaken to keep the prices confidential in return for discounts.

South Africa’s deputy director general of health, Anban Pillay, said his government had been told that $5.25 was the set price for a country classified by the World Bank as upper-middle income. “The explanation we were given for why other high-income countries have a lower price is that they have invested in the [research and development], hence the discount,” he added.

That principle has also been applied to the biggest players. The EU financially supported the development of the BioNTech and Pfizer vaccine and has obtained a lower price per dose ($14.70 than the US ($19.50). The Moderna vaccine’s development was subsidised by the US government, and it will cost the US about $15 a dose, while the EU is paying $18.

The Oxford-AstraZeneca vaccine is much cheaper, although neither the UK nor the US can match the EU’s $2.15 deal: they are expecting to pay about $3 and $4, respectively, per dose.

The Johnson & Johnson vaccine, expected to announce phase III results imminently, is also much cheaper, costing the EU $8.50, with each dose going twice as far as the other brands, since it is a single shot vaccine.

AstraZeneca and Johnson & Johnson have committed to not making a profit from the pandemic, while Moderna and Pfizer did not. AstraZeneca reserved the right, however, to declare the pandemic phase over and take profits from later vaccine sales.

Vaccine prices are only one factor in the cost of immunisation campaigns. Of the £11.7bn that the UK expects to spend on its vaccination programme, £2.9bn buys vaccines, securing 267 million doses of five different types, according to the National Audit Office.2

Even the priciest vaccines repay their cost many times over in economic growth from a reopening economy. Affluent governments could well be tempted to bid higher if supplies tighten.

Israel, which is on course to vaccinate all its citizens before any other country—having denied responsibility for vaccinating the Palestinians of the Occupied Territories—this month acknowledged paying $23.50 per dose on average to Pfizer and Moderna to obtain early shipments. Even at this high price, vaccinating the entire population of Israel costs the economy only as much as two days of lockdown. Uniquely, Israel agreed to give Pfizer anonymised health data from all of its citizens as part of the deal.

Africa secures doses
For South Africa, more troubling than the high dose cost has been an inability to secure enough vaccine. The government planned to vaccinate 40 million of its 58.5 million people but has only enough vaccine on order for 10 million.
100% bull crap
 
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POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
With your anti-EU fanaticism you are posting nonsense. As at the start of February Italy had injected 70% of all the supplies received but were suffering shortage of supplies which their PM was complaining about. AZ had just told them that they would only be delivering 40% of the contracted supply and Pfizer were delaying production so would also fall short.

And you've posted untruths about our vaccine program, claiming the oldest age group will be getting their second doses in two weeks time. I'm in that group having had my first jab in January but my second jab is scheduled for just over two months away, not two weeks.

The temporary pause in applying the AZ vaccine by some other countries is a very reasonable precaution in the circumstances when there's a possibility of harm from a treatment that hasn't been fully trialled or peer reviewed. This is especially true when the country so vigorously promoting it, Britain, is known to be so untrustworthy and led by a notorious liar.

e.g. We reached trade agreement with the EU, but as we left the EU, that PM immediately said he wouldn't necessarily keep to the agreement.

We've now broken the agreement on the conditions of trading with Northern Ireland and are refusing to comply.

We've fallen down on promises of supplies of the AZ vaccine to the EU, as the Italian example above shows, 3.4 million doses instead of 8 million.

And the claims being made for the AZ vaccine are nonsensical. Only last week AZ said they have proved it to be 100% effective. Since we have emphatic proof that it only has a very limited effect in preventing catching Covid and preventing transmission, it is very far from being 100% effective. Our own medical experts have now said they expect a surge of Covid in the Autumn, despite almost all of the population being vaccinated by then, mostly with the AZ, so clearly it is failing to fully protect.

On March 11th NHS England promised a huge increase in the vaccination program, speaking of a potential doubling to 8 million a week and bringing forward second doses. Yet now just a few days later they are already saying there will be a shortage of all supplies meaning a potential reduction of the program.

Clearly nothing said by this country is dependable and no doubt those other countries in the EU, having seen this wilful double dealing at first hand, will have that in mind when assessing the claimed safety of the AZ vaccine.

Even French Pygmies, Irish Leprechauns and the Mafiosi know liars when they meet them.
.
100% bull crap
 
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Danidl

Esteemed Pedelecer
Sep 29, 2016
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Not being a finance guy, I am not sure of the significance of this , ... But I suspect it reduces economic activity in solicitors offices .. I did have a few shares with Eircom, back in the day, and they eventually went into Vodafone, and then CREST gave me a tiny lump sum. Since it was only 300 quid to start off with,I wasn't a big loser.
From RTE...

"Securities settlement for Irish assets worth over €100 billion has left London for the European Union in the latest adjustment in markets to Brexit

Pan-European exchange Euronext, which runs the Irish stock exchange, said it had completed the migration of securities settlement for 50 Irish companies from Crest in London to Euroclear Bank in Brussels from March 15.

Settlement of EU securities must take place in a central securities depository (CSD) inside the bloc.

While the transfer does not have immediate implications for jobs and tax revenues in Britain, it is a further sign of how its financial services industry is being cut off from the EU.

The EU had given Crest temporary permission to continue settling Irish securities in London until the migration was completed. Crest is part of the Euroclear group.

The migration follows shifts in euro stock and derivatives trading from London to the bloc, with Brussels now targetting the clearing of derivatives.
 

Danidl

Esteemed Pedelecer
Sep 29, 2016
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This is a fuller section from the EMAs document... Of Yesterday, . In essence it gives the answer as to why the EMA acted as they did. Note that the initial concerns raised in Austria on 9 th March, where there was a death and a few CVT serous non fatalities, was assumed batch QC related ..from a batch which made 1M doses.
EMA’s safety committee, PRAC, concluded its preliminary review of a signal of blood clots in people vaccinated with COVID-19 Vaccine AstraZeneca at its extraordinary meeting of 18 March 2021. The Committee confirmed that:

  • the benefits of the vaccine in combating the still widespread threat of COVID-19 (which itself results in clotting problems and may be fatal) continue to outweigh the risk of side effects;
  • the vaccine is not associated with an increase in the overall risk of blood clots (thromboembolic events) in those who receive it;
  • there is no evidence of a problem related to specific batches of the vaccine or to particular manufacturing sites;
  • however, the vaccine may be associated with very rare cases of blood clots associated with thrombocytopenia, i.e. low levels of blood platelets (elements in the blood that help it to clot) with or without bleeding, including rare cases of clots in the vessels draining blood from the brain (CVST).
These are rare cases – around 20 million people in the UK and EEA had received the vaccine as of March 16 and EMA had reviewed only 7 cases of blood clots in multiple blood vessels (disseminated intravascular coagulation, DIC) and 18 cases of CVST. A causal link with the vaccine is not proven, but is possible and deserves further analysis.

The PRAC involved experts in blood disorders in its review, and worked closely with other health authorities including the UK’s MHRA which has experience with administration of this vaccine to around 11 million people. Overall the number of thromboembolic events reported after vaccination, both in studies before licensing and in reports after rollout of vaccination campaigns (469 reports, 191 of them from the EEA), was lower than that expected in the general population. This allows the PRAC to confirm that there is no increase in overall risk of blood clots. However, in younger patients there remain some concerns, related in particular to these rare cases.

The Committee’s experts looked in extreme detail at records of DIC and CVST reported from Member States, 9 of which resulted in death. Most of these occurred in people under 55 and the majority were women. Because these events are rare, and COVID-19 itself often causes blood clotting disorders in patients, it is difficult to estimate a background rate for these events in people who have not had the vaccine. However, based on pre-COVID figures it was calculated that less than 1 reported case of DIC might have been expected by 16 March among people under 50 within 14 days of receiving the vaccine, whereas 5 cases had been reported. Similarly, on average 1.35 cases of CVST might have been expected among this age group whereas by the same cut-off date there had been 12. A similar imbalance was not visible in the older population given the vaccine.

The Committee was of the opinion that the vaccine’s proven efficacy in preventing hospitalisation and death from COVID-19 outweighs the extremely small likelihood of developing DIC or CVST. However, in the light of its findings, patients should be aware of the remote possibility of such syndromes, and if symptoms suggestive of clotting problems occur patients should seek immediate medical attention and inform healthcare professionals of their recent vaccination. Steps are already being taken to update the product information for the vaccine to include more information on these risks.

The PRAC will undertake additional review of these risks, including looking at the risks with other types of COVID-19 vaccines (although no signal has been identified from monitoring so far). Close safety monitoring of reports of blood clotting disorders will continue, and further studies are being instituted to provide more laboratory data as well as real-world evidence. EMA will communicate further as appropriate.
 
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POLLY

Pedelecer
Aug 10, 2016
188
272
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This is a fuller section from the EMAs document... Of Yesterday, . In essence it gives the answer as to why the EMA acted as they did. Note that the initial concerns raised in Austria on 9 th March, where there was a death and a few CVT serous non fatalities, was assumed batch QC related ..from a batch which made 1M doses.
EMA’s safety committee, PRAC, concluded its preliminary review of a signal of blood clots in people vaccinated with COVID-19 Vaccine AstraZeneca at its extraordinary meeting of 18 March 2021. The Committee confirmed that:

  • the benefits of the vaccine in combating the still widespread threat of COVID-19 (which itself results in clotting problems and may be fatal) continue to outweigh the risk of side effects;
  • the vaccine is not associated with an increase in the overall risk of blood clots (thromboembolic events) in those who receive it;
  • there is no evidence of a problem related to specific batches of the vaccine or to particular manufacturing sites;
  • however, the vaccine may be associated with very rare cases of blood clots associated with thrombocytopenia, i.e. low levels of blood platelets (elements in the blood that help it to clot) with or without bleeding, including rare cases of clots in the vessels draining blood from the brain (CVST).
These are rare cases – around 20 million people in the UK and EEA had received the vaccine as of March 16 and EMA had reviewed only 7 cases of blood clots in multiple blood vessels (disseminated intravascular coagulation, DIC) and 18 cases of CVST. A causal link with the vaccine is not proven, but is possible and deserves further analysis.

The PRAC involved experts in blood disorders in its review, and worked closely with other health authorities including the UK’s MHRA which has experience with administration of this vaccine to around 11 million people. Overall the number of thromboembolic events reported after vaccination, both in studies before licensing and in reports after rollout of vaccination campaigns (469 reports, 191 of them from the EEA), was lower than that expected in the general population. This allows the PRAC to confirm that there is no increase in overall risk of blood clots. However, in younger patients there remain some concerns, related in particular to these rare cases.

The Committee’s experts looked in extreme detail at records of DIC and CVST reported from Member States, 9 of which resulted in death. Most of these occurred in people under 55 and the majority were women. Because these events are rare, and COVID-19 itself often causes blood clotting disorders in patients, it is difficult to estimate a background rate for these events in people who have not had the vaccine. However, based on pre-COVID figures it was calculated that less than 1 reported case of DIC might have been expected by 16 March among people under 50 within 14 days of receiving the vaccine, whereas 5 cases had been reported. Similarly, on average 1.35 cases of CVST might have been expected among this age group whereas by the same cut-off date there had been 12. A similar imbalance was not visible in the older population given the vaccine.

The Committee was of the opinion that the vaccine’s proven efficacy in preventing hospitalisation and death from COVID-19 outweighs the extremely small likelihood of developing DIC or CVST. However, in the light of its findings, patients should be aware of the remote possibility of such syndromes, and if symptoms suggestive of clotting problems occur patients should seek immediate medical attention and inform healthcare professionals of their recent vaccination. Steps are already being taken to update the product information for the vaccine to include more information on these risks.

The PRAC will undertake additional review of these risks, including looking at the risks with other types of COVID-19 vaccines (although no signal has been identified from monitoring so far). Close safety monitoring of reports of blood clotting disorders will continue, and further studies are being instituted to provide more laboratory data as well as real-world evidence. EMA will communicate further as appropriate.
COVID-19 vaccine is 100% bull crap
 
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oldgroaner

Esteemed Pedelecer
Nov 15, 2015
23,461
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If true this represents a truly immense step forward, let us sincerely hope it works out!
"
COVID-19: Science behind Pfizer-BioNTech vaccine can be used to give people cancer jabs 'within a couple of years', says co-creator
 

Zlatan

Esteemed Pedelecer
Nov 26, 2016
8,086
4,290
Well I, m glad it's all cleared up over vaccines in EU and France especially.
They are preventing anybody under 55 from having AZ, apparently they are still ignoring EMA and have decided this age group are more likely to have clots, and since the vaccine is quasi effective for over 65s they are concentrating efforts on those between 55 and 65. When interviewed, however, 52% of this age group were going to refuse AZ because it doesn't work,unless you want a blood clot.
What a joke. In mean time Paris is entering stricter lockdown and leaders there saying they don't have enough time for vaccines to slow down this current wave.. What have they done?
Oh, and in mean time 3 Scandinavian countries are, (in name of consistency??) continuing their stance of ignoring all the new data highlighted by Danidl, (that's irony Danidl) ignoring EMA and WHO and continuing their suspension of AZ.
Saying EU vaccine roll out is a shambles is an insult to the word shambles. How on earth can anyone defend this utter nightmare of the vaccine roll out.
Perhaps Danidl can churn out some data showing that AZ vaccine should be suspended by Scandinavian countries, used by others fully and used for age group 55 to 65 in France. There is nothing like EU solidarity is there. I wonder which science they are all following.Obviously quite a range of scientists, all sitting their O levels in a few years.
I don't think even Flecc or Danidl can find anything to justify this broken, inconsistent, fragmented and almost juvenile attempt.
Just remind me Flecc, what purpose exactly does EMA fulfill. Gives advice and every country, even though having agreed to joint approach and procurement, then ignores them to varying extent..
EU couldn't run a raffle.
 
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POLLY

Pedelecer
Aug 10, 2016
188
272
Chesterfield
This is a fuller section from the EMAs document... Of Yesterday, . In essence it gives the answer as to why the EMA acted as they did. Note that the initial concerns raised in Austria on 9 th March, where there was a death and a few CVT serous non fatalities, was assumed batch QC related ..from a batch which made 1M doses.
EMA’s safety committee, PRAC, concluded its preliminary review of a signal of blood clots in people vaccinated with COVID-19 Vaccine AstraZeneca at its extraordinary meeting of 18 March 2021. The Committee confirmed that:

  • the benefits of the vaccine in combating the still widespread threat of COVID-19 (which itself results in clotting problems and may be fatal) continue to outweigh the risk of side effects;
  • the vaccine is not associated with an increase in the overall risk of blood clots (thromboembolic events) in those who receive it;
  • there is no evidence of a problem related to specific batches of the vaccine or to particular manufacturing sites;
  • however, the vaccine may be associated with very rare cases of blood clots associated with thrombocytopenia, i.e. low levels of blood platelets (elements in the blood that help it to clot) with or without bleeding, including rare cases of clots in the vessels draining blood from the brain (CVST).
These are rare cases – around 20 million people in the UK and EEA had received the vaccine as of March 16 and EMA had reviewed only 7 cases of blood clots in multiple blood vessels (disseminated intravascular coagulation, DIC) and 18 cases of CVST. A causal link with the vaccine is not proven, but is possible and deserves further analysis.

The PRAC involved experts in blood disorders in its review, and worked closely with other health authorities including the UK’s MHRA which has experience with administration of this vaccine to around 11 million people. Overall the number of thromboembolic events reported after vaccination, both in studies before licensing and in reports after rollout of vaccination campaigns (469 reports, 191 of them from the EEA), was lower than that expected in the general population. This allows the PRAC to confirm that there is no increase in overall risk of blood clots. However, in younger patients there remain some concerns, related in particular to these rare cases.

The Committee’s experts looked in extreme detail at records of DIC and CVST reported from Member States, 9 of which resulted in death. Most of these occurred in people under 55 and the majority were women. Because these events are rare, and COVID-19 itself often causes blood clotting disorders in patients, it is difficult to estimate a background rate for these events in people who have not had the vaccine. However, based on pre-COVID figures it was calculated that less than 1 reported case of DIC might have been expected by 16 March among people under 50 within 14 days of receiving the vaccine, whereas 5 cases had been reported. Similarly, on average 1.35 cases of CVST might have been expected among this age group whereas by the same cut-off date there had been 12. A similar imbalance was not visible in the older population given the vaccine.

The Committee was of the opinion that the vaccine’s proven efficacy in preventing hospitalisation and death from COVID-19 outweighs the extremely small likelihood of developing DIC or CVST. However, in the light of its findings, patients should be aware of the remote possibility of such syndromes, and if symptoms suggestive of clotting problems occur patients should seek immediate medical attention and inform healthcare professionals of their recent vaccination. Steps are already being taken to update the product information for the vaccine to include more information on these risks.

The PRAC will undertake additional review of these risks, including looking at the risks with other types of COVID-19 vaccines (although no signal has been identified from monitoring so far). Close safety monitoring of reports of blood clotting disorders will continue, and further studies are being instituted to provide more laboratory data as well as real-world evidence. EMA will communicate further as appropriate.
COVID-19 vaccine is 100% bull crap
 
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