Brexit, for once some facts.

oyster

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Nov 7, 2017
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BBC Breakfast but you can google it if you like. We have 5 cases of CSVT of whom, one person died. 13 cases in the EU.
In view that we use more doses of AZ than the EU, these cases may be under reported in the UK.

EMA people reviewed the cases and in their judgement, there is not enough evidence linking AZ with CVST. They say there may be, but currently not enough. So their position is to continue with the AZ and keep an eye out for those incidents.
A note for you if you are interested, they are watching women under 55 taking the AZ.

QUOTE from EMA:

  • the benefits of the vaccine in combating the still widespread threat of COVID-19 (which itself results in clotting problems and may be fatal) continue to outweigh the risk of side effects;
  • the vaccine is not associated with an increase in the overall risk of blood clots (thromboembolic events) in those who receive it;
  • there is no evidence of a problem related to specific batches of the vaccine or to particular manufacturing sites;
  • however, the vaccine may be associated with very rare cases of blood clots associated with thrombocytopenia, i.e. low levels of blood platelets (elements in the blood that help it to clot) with or without bleeding, including rare cases of clots in the vessels draining blood from the brain (CVST).
What is the advice for an individual who receives the AZ vaccine? Any specific time? Or signs and symptoms? What should they do if the suspect an issue? Or will it be too late?
 
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Jesus H Christ

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Dec 31, 2020
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People who cannot absorb vitamin B12 (as in Pernicious Anaemia) often have very frequent injections - up to every day. Often self-administered.

From time to time, I have read of reports where they have unexpectedly felt as if some of the injected liquid has squirted back out. The usual explanation is they have hit a blood vessel and blood from that is what is coming out. (B12 is red and can look like blood. Hence some confusion.)

But that is a much larger volume.

I believe a competent injector would have cleaned her arm up on the basis of biohazard alone. You do not want drips of blood on the chair, floor, etc.

I absolutely DO NOT believe that "it is a good sign". If just from hitting a blood vessel, possibly of no impact. But I too would want to know more.

Previously have mentioned that I am keeping an eye on a long thread of vaccine experiences. At least a couple of hundred posts now. And not one single person has reported this experience. Does that mean all of them were not as good because they didn't have this sign?

I didn't even need the tiniest pad of cotton wool. It just went in and stayed in. :)
It’s tricky to determine exactly what has gone off with my wife. We’ve sent a factual account of the experience to our GP and asked for his advice. I’ll wait and see what comes back.

As a minimum I’m of the opinion she needs an antibody test.
 

Jesus H Christ

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What a very strange thing to say! that is a short term view if you don't prevent people getting infected they are likely to pass this on and a new variant that's resistant to the vaccine appear.
It’s not known whether new vaccine resistant variants are more or less likely to develop in people who have received one dose. You certainly don’t know.
 

Zlatan

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Nov 26, 2016
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What a very strange thing to say! that is a short term view if you don't prevent people getting infected they are likely to pass this on and a new variant that's resistant to the vaccine appear.
It's not strange at all OG.
Its felt by many that vaccines, whether one or 2 jabs, will not stop infection. They are known to prevent serious illness and death.
At the moment the priority is to prevent as much as that as possible, with the jab delay being a good mechanism to do so.
And, not having delay would still have no more pronounced affect on infection anyway. Yes, those with 2 jabs may transmit less efficiently but there is half as many of them.
Like I keep saying, for goodness sake just let JCVI make their decisions and get on with it.
We, ve seen what happens in EU when you let less knowledgeable folk make the decisions. Dithering, stop and starting.
Just leave it to JCVI, Mhra. They know way more, than even you (and Woosh and Flecc).
Contrary to some thoughts, I, ve only witnessed on here, JCVI and Mhra are doing a fantastic job.
 
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oldgroaner

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It comes down to the simple question. For every 1000 people, do you want to give 500 full protection and leave 500 vulnerable to death? Or do you want to protect all 1000 from death but not infection? You can’t have both because it takes a period of time to deliver 100000000 doses of vaccine.

Why are you such a Bell-end when it comes to this subject? Surely even you can see why it’s being done?
and if supplies of vaccine are sufficient there isn't a problem is there?
And if people reach the end of the 12 weeks and are vaccinated, you are back to a square one situation, except for the fact you may have a new variant to deal with as well.
The extra delay was a stupid approach to kid the gullible, and have the advantage of covering up that the government either haven't ordered enough or cant get enough supplies.
Suspiciously when the government warned of shortages
The supplier responded
"We supplied what you ordered, when you wanted it to arrive"
Now, even you can work the meaning out of that
The Government never planned to stick to the recommended dosage interval
because when you've turned a pandemic into a disaster , the only way to kid the dumb among the public is to claim you have injected Millions, when in fact you have only done half the job
And all it does is at best kick the can down the road, and you end up perpetuating the same bad idea because you still haven't organised a sufficient dupply, even though boasting of having a huge surplus of millions of doses you will never need.

And do try not to resort to this sort of response, you'll upset Zlatan's sensitivity
 

oldgroaner

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It’s not known whether new vaccine resistant variants are more or less likely to develop in people who have received one dose. You certainly don’t know.
If it hasn't as the Danish report suggested induced enough protection, then your answer is totally wrong, as every new case of infection is known to increase that risk
 

Jesus H Christ

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Dec 31, 2020
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and if supplies of vaccine are sufficient there isn't a problem is there?
And if people reach the end of the 12 weeks and are vaccinated, you are back to a square one situation, except for the fact you may have a new variant to deal with as well.
The extra delay was a stupid approach to kid the gullible, and have the advantage of covering up that the government either haven't ordered enough or cant get enough supplies.
Suspiciously when the government warned of shortages
The supplier responded
"We supplied what you ordered, when you wanted it to arrive"
Now, even you can work the meaning out of that
The Government never planned to stick to the recommended dosage interval
because when you've turned a pandemic into a disaster , the only way to kid the dumb among the public is to claim you have injected Millions, when in fact you have only done half the job
And all it does is at best kick the can down the road, and you end up perpetuating the same bad idea because you still haven't organised a sufficient dupply, even though boasting of having a huge surplus of millions of doses you will never need.

And do try not to resort to this sort of response, you'll upset Zlatan's sensitivity
You are beyond help.
 
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Danidl

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Sep 29, 2016
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You have made that argument numerous times along with OG. Yes, it perhaps has validity but exactly what insight do yourself and others have that JCVI do not.
Its a very presuming position to take, ie you know more about risk and rewards than who ever is making the decisions.
Last week you were arguing to ignore EMA, JCVI and WHO, this week over one aspect you are agreeing with their decision on one matter but disagreeing on another.
Who and JCVI have both endorsed extended delay for Pfizer and AZ.
Like I keep saying. I see those organisations has having expertise and experience to make these difficult decisions. You, me, OG, Flecc, Woosh or JHC do not.
I listen to what they say. Perhaps we all should. They are not lackeys at the disposal of governments.
It was a view expressed in the BMJ. Unfortunately, you are choosing to discount facts when making your argument. I have described in sufficient detail the processes by which both the WHO and the EMA made their holding statements while they went around their work. ... What I did not appreciate then was how rare the cerebral blood clots which occured in Norway actually were, and why they should have required investigation.
And yes I have faith in the expertise of experts, . The behaviour of our own CMO, NEPHT , ,the EMA, even our HSE has merited it.
Whether you wish to acknowledge it or not, the UK official bodies are now tainted by association with previous bad policies. A lost reputation is very slow to recover.
 
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Jesus H Christ

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If it hasn't as the Danish report suggested induced enough protection, then your answer is totally wrong, as every new case of infection is known to increase that risk
The Danes are ridiculous. They all walk around in capes made out of bacon and wear pastry hats. Take no notice.

JVT is who you should listen to. He was right about the Oxford vaccine being safe.
 

oldgroaner

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Nov 15, 2015
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It's not strange at all OG.
Its felt by many that vaccines, whether one or 2 jabs, will not stop infection. They are known to prevent serious illness and death.
At the moment the priority is to prevent as much as that as possible, with the jab delay being a good mechanism to do so.
And, not having delay would still have no more pronounced affect on infection anyway. Yes, those with 2 jabs may transmit less efficiently but there is half as many of them.
Like I keep saying, for goodness sake just let JCVI make their decisions and get on with it.
We, ve seen what happens in EU when you let less knowledgeable folk make the decisions. Dithering, stop and starting.
Just leave it to JCVI, Mhra. They know way more, than even you (and Woosh and Flecc).
Contrary to some thoughts, I, ve only witnessed on here, JCVI and Mhra are doing a fantastic job.
If you have as I pointed out in another post obtained enough supplies there isn't a problem, do you really think that Pfizer, knowing that the injections should be only a month apart, didn't plan their production to match the demand?

Rubbish! no company with their experience does that.

Remember too that when the Government blamed them for shortages they replied
"We supplied what you ordered in on the day you wanted it!"

We are in this situation because the government needed to claw back some popularity to give joe public numbers to be fooled by and be proud of.
 
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oldgroaner

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Nov 15, 2015
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The Danes are ridiculous. They all walk around in capes made out of bacon and wear pastry hats. Take no notice.

JVT is who you should listen to. He was right about the Oxford vaccine being safe.
Do try not to nod off the Danes were researching the pfizer vaccine not the AZ :D
 

Woosh

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May 19, 2012
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What is the advice for an individual who receives the AZ vaccine? Any specific time? Or signs and symptoms? What should they do if the suspect an issue? Or will it be too late?
EMA reported 9 deaths mostly in women under 55, so there may be links to other medications like contraception pills.
So watch out if you have persistent headache.
I had no symptom.
 

Danidl

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Sep 29, 2016
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He, s learning from EU..

Woosh
I believe the first AZ vaccine in a non trial situation was administered on 7th December. Since that date approx 17 million further doses have been given in Europe. Every negative aspect, every side effect was passed on to EMA/JCVI at time it occurred (or shortly after)
The Danish(I think) were first to ignore EMA 8 days ago and suspend AZ roll out.
So, in the past week or so
A) where has your extra data arrived from.
B) exactly which in depth medical study can be done in 5 days?

This has been a complete political exercise.
They had an extra weeks data ( an extra 1% or so?)
And, irrelevant to the non existent extra data they have not changed their stance.
They said it was safe last week and have simply repeated that, and added common sense platitude. "If you develop headache that lasts 4 days or suffer bruising go to your doctor".. Well I never. What top advice. And, I believe that originated from JCVI?
And the by product of it all... Further loss of confidence in AZ throughout Europe, lots of disappointed people and no inroads for a week in fight against pandemic. Its been a farce.
As for Danidl's comment re UK losing respect. Utter rubbish. EU have egg dribbling down their faces, they have proven EMA to be utterly pointless, 13 governments have proven fickle and dithering.
They could scrap EMA and it wouldn't make a jot of difference. Its shown EU and certain countries within it exactly what they are.

Rumour is they have had to find a particularly small needle for Micron. He, s having his jab today. The Quasi effective one as well. The one he suspended against EMA's advice a week ago,but like the turncoat he is, he can also say. "EMA reassessed the same data and came to same conclusion so I believe them now"
Pathetic.
Somebody really should ask him what is difference between believing EMA this week and ignoring them last? With absolutely nothing new or different emerging. Micron, like many on here, has changed his opinion with zero change of information. For posters that's just irrational. For a President it's inexcusable. He had a duty to listen last week.

Z... You continue to voice the same untruth. The data is different now. It has been checked,not supposed, not inferred, but checked. If you cannot see that as a quantitative difference, well there is little hope for you. The EMA had access to 6 M AZ cases and access to 47M Pfizer, They are in a better position on 17 th March than they were on March 12th.
As light relief, you have a hankering for a Range Rover to pull your dingy, then you see the Audi Q7 at a good price, so you test drive both, you go home do the financial sums and even though the Q7 is a few quid less, you still fancy the Range Rover and buy it.. Was that excercise a waste?. Or do you have this quiet confidence that you have done your homework, and there are no niggling doubts?
 
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Zlatan

Esteemed Pedelecer
Nov 26, 2016
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It was a view expressed in the BMJ. Unfortunately, you are choosing to discount facts when making your argument. I have described in sufficient detail the processes by which both the WHO and the EMA made their holding statements while they went around their work. ... What I did not appreciate then was how rare the cerebral blood clots which occured in Norway actually were, and why they should have required investigation.
And yes I have faith in the expertise of experts, . The behaviour of our own CMO, NEPHT , ,the EMA, even our HSE has merited it.
Whether you wish to acknowledge it or not, the UK official bodies are now tainted by association with previous bad policies. A lost reputation is very slow to recover.
How ironic. What about confidence in AZ vaccine.
Can't find it now, I, ll have a search but apparently French take up for vaccine a month ago was estimated (by survey) at 40%. That rose quickly to 70%, report suggested as a consequence of UK roll out. Yesterday it had dropped back to 49%...with Paris just entering severe lockdown and cases running at around ten times those in London, along with seriously ill being taken on train to less affected areas of country. Hardly a scenario to suspend roll out for nothing and destroy confidence further.???
In mean time you are worried about some UK authority nobody has heard of losing respect... Mmm. Priorities a bit out there Danidl.
 

Danidl

Esteemed Pedelecer
Sep 29, 2016
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It’s not known whether new vaccine resistant variants are more or less likely to develop in people who have received one dose. You certainly don’t know.
Of course. There are no guarantees in this business..however experience with bacteria and antibiotics gives little comfort. And I can assure you with my experience of dealing with lung infections in my son over decades, it is something some of us are very aware of. The closest to a miracle "cure " , was a few years ago when he had been steady going downhill for weeks with amongst other things MRSA on top of Pseudomonia, and I brought him to the hospital. They tried a very new type of antibiotic. Within 2 hours of the drip, I could see the physical improvement. Unfortunately it is now less effective.
 

Jesus H Christ

Esteemed Pedelecer
Dec 31, 2020
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How ironic. What about confidence in AZ vaccine.
Can't find it now, I, ll have a search but apparently French take up for vaccine a month ago was estimated (by survey) at 40%. That rose quickly to 70%, report suggested as a consequence of UK roll out. Yesterday it had dropped back to 49%...with Paris just entering severe lockdown and cases running at around ten times those in London, along with seriously ill being taken on train to less affected areas of country. Hardly a scenario to suspend roll out for nothing and destroy confidence further.???
In mean time you are worried about some UK authority nobody has heard of losing respect... Mmm. Priorities a bit out there Danidl.
It makes perfect sense, when suspending use of the Oxford is viewed as the political decision that it was.
 
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