Wow, some differing opinions here. Though I'd throw mine in.
Firstly the Nexus isn't totally maintenance free. It runs as a sealed unit and is greased, unlike the £1,000 Rohloff which runs in an oil bath which can be drained and refilled in situ. The Nexus will need to be re-greased every 2yrs or 5,000km according to Shimano. That might put some off as I'm sure lots of e-bikers do more than 5,00km a year. There are various versions of the Shimano Hub gear, the 8 Speed Nexus being just one. Shimano have recently launched a 5 speed hub gear aimed at the E-Bike market. The internals are more heavy duty according to the Shimano propaganda. But is 5 gears enough? They will be more widely spaced, which I personally would not like. I run a 10 speed derailleur setup on my converted e-bike and occasionally I could do with a couple more. But my wife might prefer fewer gears, she isn't.................er.......... intuitive, always changing gear too late and sometimes the wrong way, so she might get on better with 5 than her current 9. It's curious, when she drove a manual car, she didn't try to go up steep hills in top gear. Perhaps she's driven an automatic for too long.
With most crank motors having sensors to reduce power when changing gear, I really don't think the load during changes is an issue. Another feature of the top end hub gears is the electronic gear change option. Many would find this a benefit.
I have ridden the 8 Speed Nexus on an ebike. It was great, I loved it. It was hilly. (Bavarian Alps) Its cleaner too, most quality ebikes have chain guards and there are fewer external movings parts exposed to road dirt. Most commuter/city/touring ebikers would find this an attractive feature.
I see Raleigh offer an 8 speed Nexus ebike at a premium of £100, which doesn't sound too bad to me.
As for the efficiency argument, that intrigues me. A derailleur in perfect tune and clean is pretty efficient when the chain is in a fairly straight line. ie the middle three or four gears. I'll now see if I can find some tests comparing IHG with derailleur so I can help my wife make an informed choice when I decide to buy her a new bike!