Jerry - have you selected the right port? On the initial screen bottom right hand corner you'll see a drop down box containing com3, com6 etc.
Open the software WITHOUT the cable connected - it should only show one or two ports. Now shut the software, plug the cable in, wait ten secs, open the software - you should see a new port in the list - select it and try uploading again.
Open the software WITHOUT the cable connected - it should only show one or two ports. Now shut the software, plug the cable in, wait ten secs, open the software - you should see a new port in the list - select it and try uploading again.