My regular not-electric semi-decent hybrid bike (700c x 35 at 65psi) has Mavic rims and DT Swiss spokes... My very similar style but much cheaper £1000 Chinese hybrid e-bike uses generic (again 700c x 35 at 65psi) Chinese wheel sets.
Carrying my 115kg weight over road and generally smooth off-road paths, typically 18-25 mile routes, I need to re-inflate my tyres before each ride, and fettle spokes on the Chinese e-bike every 100 miles - maybe once every 250 miles on the Mavic/DT Swiss wheeled bike. No major adjustments, but the slightest nudge of the wheel (a stone, odd tree-root, minor pothole) and the tyre loses 5-10psi and the spokes don't twang like they should. That didn't used to be the case when I weighed 75/80kg (although that was some time ago!).
Carrying the weight you are is IMHO pushing most regular 700c road bike/wheel limits, unless they've been especially built for the job.